Piperidine, 4-ethyl-1-[2-(4-piperidinyl)ethyl]-
4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine
CAS: 1000958-55-3
Molecular Formula: C14H28N2
Piperidine, 4-ethyl-1-[2-(4-piperidinyl)ethyl]- - Names and Identifiers
Piperidine, 4-ethyl-1-[2-(4-piperidinyl)ethyl]- - Physico-chemical Properties
| Molecular Formula | C14H28N2 |
| Molar Mass | 224.39 |
| Density | 0.893±0.06 g/cm3(Predicted) |
| Boling Point | 295.8±8.0 °C(Predicted) |
| pKa | 10.67±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09837354 |
Piperidine, 4-ethyl-1-[2-(4-piperidinyl)ethyl]- - Introduction
4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine is a chemical substance with the following properties:
1. appearance: colorless or light yellow liquid.
2. molecular formula: C15H30N2.
3. Molecular weight: 242.41g/mol.
4. melting point: 61-64 ℃.
5. Boiling point: 214-215 ℃.
6. Solubility: Soluble in ethanol, chloroform, methanol and dichloromethane and other organic solvents.
For use:
1. 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine is commonly used as an intermediate for pharmaceutical synthesis.
2. It can be used for the synthesis of pethidine antibiotics, beta-receptor blockers, alpha 1-receptor antagonists and other drugs.
For the preparation method:
The synthesis method of 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine can be carried out by the following steps:
1. Reaction of 4-piperidinyl ethanol with 4-chloro-1-ethylpiperidine to give N-(2-chloroethyl)-4-piperidinyl ethanol.
2. The reaction product of the first step is then reacted with 1-ethyl-4-piperidineacetic anhydride to generate the target product 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine.
Safety Information:
1. 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine is an organic compound, and attention should be paid to the basic safety operation specifications of chemicals when using it.
2. This compound is irritating to eyes and skin, so you should wear protective glasses and gloves when touching or operating.
3. Avoid inhaling its vapor. In order to prevent inhalation, the working environment should be well ventilated.
4. When using or handling this compound, follow relevant safety guidelines and properly store and dispose of waste.
1. appearance: colorless or light yellow liquid.
2. molecular formula: C15H30N2.
3. Molecular weight: 242.41g/mol.
4. melting point: 61-64 ℃.
5. Boiling point: 214-215 ℃.
6. Solubility: Soluble in ethanol, chloroform, methanol and dichloromethane and other organic solvents.
For use:
1. 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine is commonly used as an intermediate for pharmaceutical synthesis.
2. It can be used for the synthesis of pethidine antibiotics, beta-receptor blockers, alpha 1-receptor antagonists and other drugs.
For the preparation method:
The synthesis method of 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine can be carried out by the following steps:
1. Reaction of 4-piperidinyl ethanol with 4-chloro-1-ethylpiperidine to give N-(2-chloroethyl)-4-piperidinyl ethanol.
2. The reaction product of the first step is then reacted with 1-ethyl-4-piperidineacetic anhydride to generate the target product 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine.
Safety Information:
1. 4-Ethyl-1-(2-piperidin-4-ylethyl)piperidine is an organic compound, and attention should be paid to the basic safety operation specifications of chemicals when using it.
2. This compound is irritating to eyes and skin, so you should wear protective glasses and gloves when touching or operating.
3. Avoid inhaling its vapor. In order to prevent inhalation, the working environment should be well ventilated.
4. When using or handling this compound, follow relevant safety guidelines and properly store and dispose of waste.
Last Update：2024-04-09 20:49:11
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